博士，副教授，生物反应器工程国家重点实验室固定成员。2009年3月取得东京大学博士学位。2009年4月至2014年8月先后在东京大学和日本筑波大学做博士后研究工作。2011年4月至 2013年3月期间任职日本学术振兴会(JSPS)特别研究员。2014年11月受聘于华东理工大学生物工程学院纳米生物工程实验室团队。入选上海市浦江人才（A类），华理青年英才引进与培育计划，生工学院优秀青年教师培育计划。主持国家自然科学基金面上项目，上海市浦江人才项目，国家重点实验室开放课题等多个项目。以第一作者身份在Nature Chemical Biology, Applied Environmental Microbiology等著名期刊上发表论文多篇。
2009年4月――2014年8月东京大学、日本筑波大学博士后研究工作
2011年4月――2013年3月日本学术振兴会(JSPS)特别研究员
研究领域为环境微生物、病原微生物及工业微生物的分子生物学。探索微生物环境胁迫、信号传导及次级代谢调控等相关的诸多功能基因，活用这些基因使之服务于工业，农业，医疗卫生等领域。长期以来以模型真菌为研究对象，探索了天然免疫杀菌分子一氧化氮（NO）的杀菌机制及病原菌应对NO的抗逆机制，鉴定出一系列新型NO抗性功能基因，并阐明了其抗性原理，为新型抗真菌药物开发提供了理论基础。近期又开展了微生物氧化应激及与之对应的信号传导、细胞凋亡与衰老等相关机制研究。
1.真菌的NO抗性分子机制解析及抗真菌药物杀菌靶点的定位
2.真菌的氧化应激抗性体系的解析及新型杀菌靶点的探索
3.真菌有用次级代谢产物合成途径及其调控机制的研究
4.工业微生物生物被膜形成的分子机制及其集群效应
5.智能型丝状真菌蛋白表达体系的开发
6.活体检测生物探针的开发
(1).Yao Zhou,Shengmin Zhou*, Haijun Yu, Jingyi Li, Yang Xia, Baoyi Li, Xiaoli Wang, Ping Wang*. Cloning and characterization of filamentous fungal S-nitrosoglutathione reductase from Aspergillus nidulans.Journal of Microbiology and Biotechnology. In press, doi: 10.4014/jmb.1512.12009, Feb, 2016
(2).Jia Wei, Xiaodan Cao,Shengmin Zhou, Chao Chen, Haijun Yu, Yao Zhou, Ping Wang. Soluble expression and purification of the catalytic domain of human vascular endothelial growth factor receptor 2 in Escherichia coli.Journal of Microbiology and Biotechnology. 25(8): 1227-1233, 2015
(3).Shunsuke Masuo, Lisa Osada,Shengmin Zhou, Tomoya Fujita, Naoki Takaya. Aspergillus oryzae pathways that convert phenylalanine into the flavor volatile 2-phenylethanol.Fungal Genetics and Biology. 77: 22-30, 2015.
(4).Shengmin Zhouand Naoki Takaya. Novel fungal nitrosothionein peptide involved in tolerance to nitric oxide.Bioscience&industry. 72(2): 55-56, 2014.
(5).Masanori Toyofuku,Shengmin Zhou, Isao Sawada, Naoki Takaya, Hiroo Uchiyama and Nobuhiko Nomura. Membrane vesicle formation is associated with pyocin production under denitrifying conditions in Pseudomonas aeruginosa PAO1.Environmental Microbiology.16(9):2927-2938, Sep, 2014,
(6).Shengmin Zhou, Toshiaki Narukami, ShunsukeMasuo, Motoyuki Shimizu, Tomoya Fujita, Yuki Doi, Yosuke Kamimura, Naoki Takaya. NO-inducible nitrosothionein mediates NO removal in tandem with thioredoxin.Nature Chemical Biology. 9(10): 657-663, Aug, 2013.
(7).Tomoya Fujita, HieuDuc Nguyen, Takashi Ito,Shengmin Zhou, Lisa Osada, Seiji Tateyama, Tatsuo Kaneko, Naoki Takaya. Microbial monomers custom-synthesized to build true bio-derived aromatic polymers.Applied Microbiology and Biotechnology. 97(20):8887-8894, Aug, 2013.
(8).Wenjing Cui, Xiaoyan Yang, Yueqin Fang,Shengmin Zhou, Song Liu, Guocheng Du, Kun Du, Jian Chen, Guanjun Tao and Zhemin Zhou. Discovery of two transglutaminases derived from same zymogen for the Streptomyces hygroscopicus and analysis of their formation processes.Journal of the Science of Food and Agriculture. 93(7): 1711-1717, May, 2013.
(9).Morio Miyahara, Sang-Wan Kim,Shengmin Zhou, Shinya Fushinobu, Takeshi Yamada, Wakako Ikeda-Ohtsubo, Akira Watanabe, Keisuke Miyauchi, Ginro Endo and Hirofumi Shoun. Survival of the aerobic denitrifier Pseudomonas stutzeri strain TR2 during co-culture with activated sludge under denitrifying conditions.Bioscience, Biotechnology, and Biochemistry. 76(3): 495-500, Mar, 2012.
(10).Shengmin Zhou, Toshiaki Narukami, Misuzu Nameki, Tomoko Ozawa, Yosuke Kamimura, Takayuki Hoshino and Naoki Takaya. Heme-biosynthetic porphobilinogen deaminase protects Aspergillus nidulans from nitrosative stress.Applied and Environmental Microbiology. 78(1): 103-109, Jan, 2012.
(11).Shengmin Zhou, Shinya Fushinobu, Sang-Wan Kim, Yoshito Nakanishi, Jun-ichi Maruyama, Katsuhiko Kitamoto, Takayoshi Wakagi, and Hirofumi Shoun. Functional analysis and subcellular location of two flavohemoglobins from Aspergillus oryzae.Fungal Genetics and Biology.48(2): 200-207, Feb, 2011.
(12).Sang-Wan Kim, Shinya Fushinobu,Shengmin Zhou, Takayoshi Wakagi and Hirofumi Shoun. The possible involvement of copper-containing nitrite reductase (NirK) and flavohemoglobin in denitrification by the fungus Cylindrocarpon tonkinense.Bioscience, Biotechnology, and Biochemistry.74 (7): 1403-1407, Jul, 2010.
(13).Shengmin Zhou*, Yoshito Nakanishi*, Shinya Fushinobu, Sang-Wan Kim, Jun-ichi Maruyama, Katsuhiko Kitamoto, Takayoshi Wakagi, and Hirofumi Shoun. A eukaryotic copper-containing nitrite reductase derived from a NirK homolog gene of Aspergillus oryzae.Bioscience, Biotechnology, and Biochemistry.74(5):984-991, May, 2010.
(14).Shengmin Zhou, Shinya Fushinobu, Sang-Wan Kim, Yoshito Nakanishi, TakayoshiWakagi, and Hirofumi Shoun. Aspergillus oryzae flavohemoglobins promote oxidative damage by hydrogen peroxide.Biochemical and Biophysical Research Communications.394(3):558-561, Apr, 2010.
(15).Sang-Wan Kim, Shinya Fushinobu,Shengmin Zhou, Takayoshi Wakagi, and Hirofumi Shoun. Eukaryotic nirK genes encoding copper-containing nitrite reductase: originating from the protomitochondrion?Applied and Environmental Microbiology. 75 (9): 2652-2658, Mar, 2009.
(16).Shengmin Zhou, Shinya Fushinobu, Yoshito Nakanishi, Sang-Wan Kim, Takayoshi Wakagi and Hirofumi Shoun. Cloning and characterization of two flavohemoglobins from Aspergillus oryzae.Biochemical and Biophysical Research Communications.381 (1): 7-11, Jan, 2009.
