演讲
1999年10月晋升为教授。2002年9月被南京工业大学遴选为博士生导师；11月被鲁南制药股份有限公司聘为博士后工作站指导教师。
2003年9月被青岛科技大学遴选为博士生导师。现指导在读博士研究生9人，硕士研究生10人。
2012年7月调至临沂大学工作。
2015年至今任临沂大学校长。
曾任青岛科技大学化学与分子工程学院院长。现任临沂大学学术部部长兼科技处处长。
主要成就科研成就2003年以来，作为项目负责人承担课题9项，其中：国家自然科学基金2项，教育部新世纪优秀人才支持计划1项，
青岛市科技将才专项计划1项，电分析化学国家重点实验室基金1项，山东省自然科学基金-重点项目2项，山东省优秀中青年科学家奖励基金2项，山东省教育厅科技计划1项，青岛市科技发展规划1项。
2005年6月通过山东省科技厅组织的鉴定项目1项。
2006年5月通过山东省教育厅组织的鉴定项目1项。
申报发明专利32项，已进入实审21项。出版专(译)著4部。
2002年以来在国际国内重要学术刊物上发表第一作者SCI收录论文40篇，代表论文如下：
1. Sai Bi, Yameng Yan, Shuangyuan Hao, Shusheng Zhang*
Colorimetric Logic Gates Based on Supramolecular Constructs of DNAzymes Responding to Ion Input Signals
Angew. Chem. Int. Ed., 2010, 49(26): 4438~4442（IF=11.829）
2. Wei Wang, Lin Li, Shufeng Liu, Cuiping Ma, Shusheng Zhang*
Determination of physiological thiols by electrochemical detection with piazselenole and its application in rat breast cancer cells 4T-1
J. Am. Chem. Soc., 2008, 130: 10846~10847（IF=8.58）
3. Xuemei Li, Xiaoyan Yang, Shusheng Zhang*
Electrochemical enzyme immunoassay using model labels
Trends in Anal. Chem., 2008, 27(6): 543~553（IF=6.546）
4. Kongcheng Hu, Dongxiao Lan, Xuemei Li, Shusheng Zhang*
Chronocoulometric Detection of DNA Hybridization Using reporter DNA Probe Modified with Au Nanoparticles Based on porous gold leaf electrode
Anal. Chem., 2008, 80: 9124~9130（IF=5.214）
5. Caifeng Ding, Xiangling Li, Ying Ge, Shusheng Zhang*
Ultrasensitive Fluorescence Detection of Telomerase Activity in Cancer Cells Based on Isothermal Circular Strand-displacement Polymerization Reaction
Anal. Chem., 2010, 82 (7): 2850~2855（IF=5.214）
6. Sai Bi, Li Li, Shusheng Zhang*
Triggered Polycatenated DNA Scaffolds for DNA Sensors and Aptasensors by a Combination of Rolling Circle Amplification and DNAzyme Amplification
Anal. Chem., 2010, 82(22): 9447~9454（IF=5.214）
7. Guifen Jie, Lei Wang, Jinxin Yuan, Shusheng Zhang*
Versatile Electrochemiluminescence Assays for Cancer Cells Based on Dendrimer/CdSe-ZnS-Quantum Dot Nanoclusters
Anal. Chem., 2011, doi: 10.1021/ac200383z（IF=5.214）
8. Shu-sheng Zhang*, Hua Zhong, Cai-feng Ding*
Ultrasensitive Flow Injection Chemiluminescence Detection of DNA Hybridization Using signal DNA probe modified with NanoAu and NanoCuS Tags
Anal. Chem., 2008, 80(19): 7206~7212（IF=5.214）
9. Shu-Sheng Zhang*, Jian-ping Xia, Xue-Mei Li*
Electrochemical Biosensor for Detection of Adenosine Based on Structure-Switching Aptamer and Amplification with Reporter Probe DNA Modified Au Nanoparticles
Anal. Chem., 2008, 80 (22): 8382~8388（IF=5.214）
10. Shu-sheng Zhang*, Ya-meng Yan, Sai Bi*
Design of Molecular Beacon as Signaling Probes for ATP Detection in Cancer Cells Based on Chemiluminescence Resonance Energy Transfer
Anal. Chem., 2009, 81(21): 8695~8701（IF=5.214）
11. Sai Bi, Yameng Yan, Xiaoyan Yang, Shu-sheng Zhang*
Gold Nanolabels for New Enhanced Chemiluminescence Immunoassay of Alpha-fetoprotein Based on Magnetic Beads
Chem.-Euro. J., 2009, 15: 4704~4709（IF=5.382）
12. Caifeng Ding, Ying Ge, Shu-sheng Zhang*
Electrochemical and Electrochemiluminescence Determination of Cancer Cells Based on Aptamers and Magnetic Beads
Chem.-Euro. J., 2010, 16: 10707~10714（IF=5.382）
13. Hui Zhang, Congcong Fang, Shusheng Zhang*
Electrochemical Determination of Adenosine Triphosphate in Cancer Cells Amplified with Autonomous Bio-bar-code DNA Machine
Chem.-Euro. J., 2010, 16: 12434~12439（IF=5.382）
14. Guifen Jie, Lei Wang, Shusheng Zhang*
Magnetic Electrochemiluminescent Hybrid Nanostructures of Fe3O4/CdSe@CdS-Quantum Dots/ Polyelectrolytes for Highly Efficient Immunosensing of Cancer Biomarker Protein
Chem.-Euro. J., 2011, 17: 641~648（IF=5.382）
15. Hui Zhang, Congcong Fang, Shusheng Zhang*
Ultrasensitive Electrochemical Analysis of Two-component Analytes by An Autonomous DNA Machine Worked in Two-cycle Modes
Chem.-Euro. J., 2011, 17(27) : 7531~7537（IF=5.476）
16. Xue-mei Li, Jinming Liu, Shu-sheng Zhang*
Electrochemical Biosensor for Simultaneous Analysis of Two Analytes Based on a Dual-Aptamer DNA Sequence
Chem. Commun., 2010, 46: 595~597（IF=5.504）
17. Rui Ren, Cuicui Leng, Shusheng Zhang*
A Cell sensor based on aptamer recognition and electrode-based circular strand-replacement DNA polymerization
Chem. Commun., 2010, 46: 5758 - 5760（IF=5.504）
18. Hua Zhong, Xi Lei, Xu Hun, Shu-sheng Zhang*
Design of One-to-one Recognition DNA Probe Based on Triple Au Nanoparticles Bio Bar Codes and its Application in the Electrochemical DNA Biosensor
Chem. Commun., 2009, 45: 6958~6960（IF=5.504）
19. Yingshu Guo, Xueping Jia, Shusheng Zhang*
DNA cycle amplification device on magnetic microbeads for determination of thrombin based on graphene oxide enhancing signal-on electrochemiluminescence
Chem. Commun., 2011, 47(2): 725~727（IF=5.504）
20. Yingshu Guo, Yuanshun Sun, Shusheng Zhang*
Electrochemiluminescence induced photoelectrochemistry for sensing of the DNA based on DNA-linked CdS NPs superstructure with intercalator molecules
Chem. Commun., 2011, 47 (5): 1595~1597（IF=5.504）
21. Sai Bi, Hong Zhou, Shu-sheng Zhang*
Ultrasensitive Flow Injection Chemiluminescence Detection of DNA Hybridization Based on Bio-Bar-Code Functionalized Magnetic Nanoparticle Label
Chem. Commun., 2009, 37: 5567~5569（IF=5.504）
22. Sai Bi, Shuangyuan Hao, Li Li, Shusheng Zhang*
Bio-Bar-Code Dendrimer-like DNA as Signal Amplifier for Cancerous Cells Assay Using Ruthenium Nanoparticle-Based Ultrasensitive Chemiluminescence Detection
Chem. Commun., 2010, 46: 6093~6095（IF=5.504）
23. Caifeng Ding, Hui Li, Xiangling Li, Shusheng Zhang*
A new strategy of photoelectrochemical analysis with light source free based on isoluminol labelled chemiluminescence probe
Chem. Commun., 2010, 46(42): 7990~7992（IF=5.504）
24. Guifen Jie, Ping Liu, Shusheng Zhang*
Highly Enhanced Electrochemiluminescence of Novel Gold/Silica/CdSe-CdS Nanostructures for Ultrasensitive Immunoassay of Protein Tumor Marker
Chem. Commun., 2010, 46: 1323~1325（IF=5.504）
25. Sai Bi, Jilei Zhang, Shusheng Zhang*
Ultrasensitive and Selective DNA Detection Based on Nicking Endonuclease Assisted Signal Amplification and Its Application in Cancer Cell Detection
Chem. Commun., 2010, 46: 5509~5511（IF=5.504）
26. Chunxiang Li, Juan Lin, Yingshu Guo, Shusheng Zhang*
An Electrochemiluminescent Reagent of Cyclometalated Iridium Complex-Based DNA Biosensor and its Application in Cancer Cell Detection
Chem. Commun., 2011, 47 (15): 4442~4444（IF=5.787）
27. Xiaoru Zhang, Shuguo Li, Xia Jin, Shusheng Zhang*
New Photoelectrochemical Aptasensor for the Thrombin Detection Based on Functionalized Graphene and CdSe Nanoparticles Multilayers
Chem. Commun., 2011, 47 (17): 4929~4931（IF=5.787）
教学成就长期以来一直从事教学、科研工作。
社会活动2012年8月担任山东省首席专家。
2017年1月张书圣科技领军人才创新工作室揭牌。[2]
2015年入选泰山学者攀登计划[1]。
担任生态化工教育部重点实验室主任，生态化工国家重点实验室培育基地主任，山东省生化分析重点实验室主任，《分析化学》编委。
获得荣誉时间奖项全称具体奖项获奖作品颁奖机构2013年教育部自然科学奖二等奖（第一位）2011年11月“长江学者及创新团队发展计划”创新团队奖创新团队奖生化分析团队2011年青岛市优秀共产党员荣誉称号2010年10月青岛市优秀创新团队优秀创新团队应用化学团队2010年4月东省自然科学奖二等奖（首位）