李金恒

李金恒出生于湖南永州。

2011–至今?湖南大学，教授，博士生导师

2001–2010?湖南师范大学，教授，博士生导师

2002–2004?香港大学博士后

2000–2001?中国科学院广州化学研究所助研

2000–2002?中国科学技术大学（在职）博士学位

1997–2000?中国科学院广州化学研究所硕士学位

1994–1997?湖南农业大学助教

1990–1994?湖南师范大学学士学位

（1）国家自然科学基金青年项目“非临界二氧化碳调控有机反应的研究”（No.?20202002,?2003.1?–?2005.12）。

（2）国家自然科学基金面上项目“胺作为配体在钯催化交叉偶联反应中应用研究”（No.?20572020,?2006.1?–?2008.12）。

（3）国家自然科学基金面上项目“芳基不饱和烃分子内亲电自位环?化反应合成螺环化合物的研究”（No.?20872112,?2009.1-20011.12）。

（4）教育部2006年度新世纪优秀人才支持计划“过渡金属催化偶联反应中几个基本问题的研究”（No.?NCET-06-0711，2007.01?-?2009.12）

（5）霍英东教育基金会第十届高等院校青年教师基金“叔胺作为配体在钯催化偶联反应中应用研究”（No.?101012，2006.?3?-?2008.?3）

（6）教育部2006年度高等学校博士学科点专项科研基金项目“钯和卤化铜为催化体系的炔烃卤钯化反应及其在有机合成中应用研究”（No.?20060542007，2007.01?-?2009.12）

（7）教育部科学技术研究重点项目“叔胺作为配体在钯催化交叉偶联反应中应用研究”（No.?206102，2006.01?~?2007.12）。

（8）湖南省杰出青年基金项目“蛋白酶抑制剂3-亚甲基吲哚-2-酮衍生物合成新方法炔烃羰基化反应研究”（No.?05JJ1002,?2005.1?–?2007.12）。

（9）湖南省教育厅项目“过渡金属催化炔芳构化反应研究”（No.?02C211，2003.01-2004.12）。

（10）湖南省教育厅优秀青年项目“叔胺作为配体在钯催化交叉偶联反应中应用研究”（No.?05B038，2005.01?–?2006.12）。

（11）湖南省教育厅重点项目“芳基不饱和烃分子内亲电自位环化反应合成螺环化合物的研究”（8?万，08A037,?2009-2011）。

（12）2008年浙江省科技计划面上项目“抗肿瘤靶向药物3-亚甲基吲哚酮合成技术开发与应用研究”（No.?2008C33065，2008.01?-?2008.12）

（13）化学生物传感与计量学国家重点实验室（湖南大学）项目“具有荧光特性的卟啉类化合物合成方法研究”（No.?2006016,?2007.?3?-?2009.?3）。

2017年，湖南省科学技术奖自然科学奖一等奖；[1]

2010年，广东省科学技术奖一等奖（第四完成人）；

2009年度，获湖南省科学技术奖自然科学奖二等奖1项（第一完成人，项目名称：过渡金属钯、铜催化构建C-C键和C-N键方法的研究）；

2006年度，湖南省自然科学优秀学术论文一等奖；

2004年度，湖南省自然科学优秀学术论文一等奖；

2001年度，中国科技大学“张宗植“科技奖学金；

2000年度，中国科学院“院长优秀奖”奖学金；

1999年度，中国科学院“伟华”科技奖学金。

主要研究兴趣在有机合成方法学、金属有机化学、药物合成和绿色化学等几方面：

（1）过渡金属催化交叉偶联反应；

（2）过渡金属催化氧化环化串联反应；

（3）应用发展出新的合成方法和技术，合成出具有抗肿瘤活性的靶向药物。

1?Zhi-Qiang?Wang,?Yong?Lei,?Ming-Bo?Zhou,?Guo-Xiang?Chen,?Ren-Jie?Song,?Ye-Xiang?Xie,?and?Jin-heng?Li,*?Iron-Mediated?[3+2]?or?[3+3]?Annulation?of?2-(2-(Ethynyl)phenoxy)-1-arylethanones:?Selectivesynthesis?of?Indeno[1,2-c]chromenes?and?5H-Naphtho[1,2-c]chromenes,?Org.?Lett.?2011,?13,?14-17.

2?Yan?Liu,?Bo?Yao,?Chen-Liang?Deng,*?Ri-Yuan?Tang,?Xing-Guo?Zhang,?and?Jin-Heng?Li,*?Palladium-catalyzed?Selectiveheck-Type?Diarylation?of?Allylic?Esters?with?Aryl?Halides?Involving?a?β-OAC?Elimination?Process,?Org.?Lett.,?2011,?13,?1126–1129.

3?Liu,?Y.;?Yao,?B.;?Deng,?C.-L.;*?Tang,?R.-Y.;?Zhang,?X.-G.;?Li,?J.-H.*?Palladium-Catalyzed?Oxidative?Coupling?of?Trialkylamines?with?Aryl?Iodides?Leading?to?Alkyl?Aryl?Ketones,?Org.?Lett.,?2011,?13,?2184-2187.

4?Yong?Lei,?Zhi-Qiang?Wang,?Ye-Xiang?Xie,?Shang-Ci?Yu,?Bo-Xiao?Tang,?and?Jin-Heng?Li,*?Base-Mediated?Tandem?Reaction?Consisting?of?An?Acyl?Shift?Strategy?Leading?to?4,5-Disubstiuted?Furan-2(5H)-ones,?Adv.?Synth.?Catal.?2011,?353,?31-35.

5?Huang-Che?Ouyang,?Ri-Yuan?Tang,?Ping?Zhong,*?Xing-Guo?Zhang,?and?Jin-Heng?Li*?CuI/I2-Promoted?Electrophilic?Tandem?Cyclization?of?2-Ethynylbenzaldehydes?with?ortho-Benzenediamines:?Synthesis?of?Iodoisoquinoline-fused?Benzimidazoles,?J.?Org.?Chem.?2011,?76,?223-226.

6?Ren-Jie?Song,?Yu?Liu,?Yan-Yun?Liu,?and?Jin-Heng?Li,*?Palladium-Catalyzedconjugate?Addition?to?Electron-deficient?Alkynes?with?Benzenesulfinic?Acid?Derived?from?1,2-Bis(phenylsulfonyl)ethane:?Selective?Synthesis?of?(E)-Vinyl?Sulfones,?J.?Org.?Chem.?2011,?76,?1001–1004.

7?Hong-Ping?Zhang,?Shang-Ci?Yu,?Yun,?Liang,?Peng?Peng,?Bo-Xiao?Tang,?and?Jin-Heng?Li*?Halopalladation?Cyclization?of?Alkynes?with?Azides:?Selective?Synthesis?of?4-Haloisoquinolines?and?3-Haloindoles,?Synlett?2011,?982-988.

8?Xiao-Li?Fang,?Ri-Yuan?Tang,?Xing-Guo?Zhang,*?and?Jin-Heng?Li*,?FeF3/I2-Catalyzed?Synthesis?of?4-Chalcogen-Substituted?Arylamines?by?Direct?Thiolation?of?an?Arene?C-H?Bond,?Synthesis?2011,?1099-1105.

9?Hong-Ping?Zhang,?Xu-Heng?Yang,?Peng?Peng,?and?Jin-Heng?Li,*?PdI2/I2-Catalyzed?Thiolation?Annulations?of?2-Alkynyl?Benzyl?Azides?with?Disulfides:?Selective?Synthesis?of?4-Sulfenylisoquinolines,?Synthesis?2011,?1219-1226.

10?Xiao-Li?Fang,?Ri-Yuan?Tang,?Xing-Guo?Zhang,?Ping?Zhong,*?Chen-Liang?Deng,?Jin-Heng?Li*ZnCl2-catalyzed?[4+2]?benzannulation?of?2-ethynylbenzaldehydes?with?alkynes:?selective?synthesis?of?naphthalene?derivatives,?J.?Organometal.?Chem.?2011,?696,?352-356.

11?Bo-Xiao?Tang,?Ren-Jie?Song,?Cui-Yan?Wu,?Yu?Liu,?Ming-Bo?Zhou,?Wen-Ting?Wei,?Guo-Bo?Deng,?Du-Lin?Yin,?and?Jin-Heng?Li,*?Copper-Catalyzed?Intramolecular?C-H?Oxidation/Acylation?of?Formyl-N-arylformamides?Leading?to?Indoline-2,3-diones,?J.?Am.?Chem.?Soc.?2010,?132,?8900–8902.

12?Ri-Yuan?Tang,?Jin-Heng?Li,*?PdCl2-Cataylzed?Domino?Reactions?of?2-Alkynylbenzaldehydes?with?Indoles:?Synthesis?of?Fluorescent?5H-Benzo[b]carbazol-6-yl?Ketones,?Chem.?Eur.?J.?2010,?16,?4733-4738.

13?Rong-Jiang?Li,?Shao-Feng?Pi,?Yun?Liang,*,?Zhi-Qiang?Wang,?Ren-Jie?Song,?Guo-Xiang?Cheng,?and?Jin-Heng?Li*?Palladium-Catalyzed?Annulations?of?Arynes?with?2-(2-Iodophenoxy)-1-substitutedethanones?through?a-Arylation?of?Ketones,?Chem.?Commun.?2010,?46,?8183–8185.

14?Shao-Feng?Pi,?Xu-Heng?Yang,?Xiao-Cheng?Huang,?Yun?Liang,*?Guan-Nan?Yang,?Xiao-Hong?Zhang,?and?Jin-Heng?Li,*?Palladium-Catalyzed?Cyclocarbonylation?of?Arynes?with?Methyl?Allyl?Carbonates:?Selective?Synthesis?of?1H-Inden-1-ones?J.?Org.?Chem.?2010,?75,?3484–3487.

15?Wen-Wu?Zhang,?Xing-Guo?Zhang,?and?Jin-Heng?Li,*?Palladium-Catalyzed?Decarboxylative?Coupling?of?Alkynyl?Carboxylic?Acids?with?Benzyl?Halides?or?Aryl?Halides,?J.?Org.?Chem.?2010,?75,?5259-5264.

16?Ming-Bo?Zhou,?Wen-Ting?Wei,?Ye-Xiang?Xie,?Yong?Lei,?and?Jin-Heng?Li,*?Palladium-Catalyzed?Cross-Coupling?of?Electron-Poor?Terminal?Alkynes?with?Arylboronic?Acids?under?Ligand-Free?andaerobic?Conditions,?J.?Org.?Chem.?2010,?75,?5635–5642.

17?Shu-Xiang?Dong,?Xing-Guo?Zhang,*?Qiong?Liu,?Ri-Yuan?Tang,?Ping?Zhong,?Jin-Heng?Li,*?Synthesis?of?1-Substituted-2-(trifluoromethyl)indoles?via?Palladium-Catalyzed?Double?Amination?Reaction,?Synthesis?2010,?1521-1525.

18?Jian-Sheng?Tang,?Ye-Xiang?Xie,?Zhi-Qiang?Wang,?Chen-Liang?Deng,?and?Jin-Heng?Li,*?Phosphazene?Base-Catalyzed?Intramolecular?Cascade?Reactions?of?Aryl-Substituted?Enynes,?Synthesis?2010,?3204-3210.

19?Yu?Liu,?Ren-Jie?Song,?and?Jin-Heng?Li,*?Yb(OTF)3-Promoted?ZnCl2-Catalyzed?Conia-ene?Reactions?of?Linear?β-Alkynic?β-Dicarbonyls,?Synthesis?2010,?3663-3669.

20?Ri-Yuan?Tang,?Pei-Song?Luo,?Xing-Guo?Zhang,?Ping?Zhong,?and?Jin-Heng?Li,*?Silver-Catalyzed?Ammonolysis-Cyclization?Tandem?Reactions?of?2-Alkynylbenzenamines?with?Tetraalkylthiuram?Disulfides?Leading?to?4-Methylene-4H-benzo[d][1,3]thiazin-2-amines,?Synlett?2010,?1345-1350.

21?Xia?Zhao,?Xing-Guo?Zhang?Ri-Yuan?Tang,?Chen-Liang?Deng,?Jin-Heng?Li,*?ZnI2-Catalyzed?Benzannulation?of?o-Alkynylbenzaldehydes?with?Alkenes?Leading?to?1-Acyl-2-substitutednaphthalenes,?Eur.?J.?Org.?Chem.?2010,?4211-4217.

22?Yan-Jin?Guo,?Ri-Yuan?Tang,?Ping?Zhong,?Jin-Heng?Li*?Copper-Catalyzed?Tandem?Reactions?of?2-Halobenzenamines?with?Isothiocyanates?under?Ligand?and?Base-Free?Conditions,?Tetrahedron?Lett.?2010,?51,?649-652.

23?WANG?Feng,?TANG?Boxiao,?XIE?Yexiang,*?LI?Jinheng,*?Synthesis?of?Alkyl-Aryl?Ethers?by?Copper-catalyzed?Etherization?Reaction?of?Aryl?Fluorides?with?Tetraalkylammonium?Bromides?and?H2O?in?the?Presence?of?Base,?Chin.?J.?Chem.?2010,?28,?2318-2312.

24?Zhi-Qiang?Wang,?Yun?Liang,?Yong?Lei,?Ming-Bo?Zhoua?and?Jin-Heng?Li*?Iron-catalyzed?annulations?of?2-(2-alkynyl)phenoxy)-1-arylethanones?leading?to?substituted?naphthalen-1-ols,?Chem.?Commun.?2009,?5242–5244.

25?Tao-Shan?Jiang?and?Jin-Heng?Li?Palladium-catalyzed?oxidative?tandem?reaction?of?allylamines?with?aryl?halides?leading?to?unsaturated?aldehydes,?Chem.?Commun.?2009,?7236-7238.

26?Chen-Liang?Deng,?Ren-Jie?Song,?Yi-Lin-Liu,?Jin-Heng?Li,*?Gerneral?Zinc-Catalyzed?Conia-Ene?Reactions?of?1,3-dicarbonly?Compounds?with?Alkynes?Including?the?Classsically?Challenging?Substrates?under?Neat?Conditions,?Adv.?Synth.?Catal.?2009,?351,?3096–3100.

27?Yan-Jin?Guo,?Ri-Yuan?Tang,?Jin-Heng?Li,*?Ping?Zhong,?and?Xing-Guo?Zhang*?Palladium-Catalyzed?Annulation?of?2-(1-Alkynyl)benzenamines?with?Disulfides:?Synthesis?of?3-Sulfenylindoles,?Adv.?Catal.?Synth.?2009,?351,?2615-2618.

28?Jing-Wen?Qiu,?Xing-Guo?Zhang,?Ri-Yuan?Tang,?Ping?Zhong,?and?Jin-Heng?Li*?Iron-Catalyzed?Tandem?Reactions?of?2-Halobenzenamines?with?Isothiocyanates?Leading?to?2-Aminobenzothiazoles,?Adv.?Catal.?Synth.?2009,?351,?2319-2323.

29?Zou,?T.;?Pi,?S.-S.;?Li,?J.-H.*?FeCl3-Catalyzed?1,2-Addition?Reactions?of?Aryl?Aldehydes?with?Arylboronic?Acids,?Org.?Lett.?2009,?11,?453-456.

30?Huang,?X.-C.;?Wang,?F.;?Liang,?Y.;*?Li,?J.-H.*?Halopalladation/Decarboxylation/Carbon?Carbon?Forming?Domino?Process:?Synthesis?of?5-Halo-6-substituted?Benzo[b]naphtho[2,1-d]furans,?Org.?Lett.?2009,?11,?1139-1142.

31?Shao-Feng?Pi,?Bo-Xiao?Tang,?Jin-Heng?Li*,?Yi-Lin?Liu?and?Yun?Liang,*?Palladium-Catalyzed?Decarboxylative?Coupling?of?Allylic?Alkynoates?with?Arynes,?Org.?Lett.,?2009,?11,?2309-2312.

32?Deng,?C.-L.;?Zou,?T.;?Wang,?Z.-Q.;?Song?R.-J.;?Li,?J.-H.*?Copper/Silver-Cocatalyzed?Conia-Ene?Reactions?of?2-Alkynic?1,3-Dicabonyl?Compounds,?J.?Org.?Chem.?2009,?74,?412-414.

33?Liu,?Y.-L.;?Liang,?Y.;?Pi,?S.-F.;?Huang,?X.-C.;?Li,?J.-H.*?Palladium-Catalyzed?Cocyclotrimerization?of?Allenes?with?Arynes:?Selective?Synthesis?of?Phenanthrenes,?J.?Org.?Chem.?2009,?74,?3199–3202.

34?Peng,?P.;?Tang,?B.-X.;?Pi,?S.-F.;?Liang,?Y.;?Li,?J.-H.*?Synthesis?of?(E)-3-(Isobenzofuran-3(1H)-ylidene)indolin-2-ones?by?Palladium-Catalyzed?Intramolecular?C-H?Functionalization?Process,?J.?Org.?Chem.?2009,?74,?3569-3572.

35?Yi-Lin?Liu,?Yun?Liang,*?Shao-Feng?Pi,?Jin-Heng?Li*?Selective?Synthesis?of?o-Acetylbenzylphosphonates?by?Insertion?Reactions?of?Arynes?into?β-Ketophosphonates,?J.?Org.?Chem.?2009,?74,?5691-5694.

36?Dong-Jun?Tang,?Bo-Xiao?Tang,?and?Jin-Heng?Li*?Selective?Synthesis?of?3-Aryl?Quinolin-2(1H)-ones?and?3-(1-Arylmethylene)oxindoles?Involving?a?2-Fold?Arene?C-H?Activation?Process,?J.?Org.?Chem.?2009,?74,?6749–6755.

37?Hui-Ai?Du,?Xing-Guo?Zhang*,?Ri-Yuan?Tang,?and?Jin-Heng?Li*?PdCl2-Promoted?Electrophilic?Annulation?of?2-Alkynylphenol?Derivatives?with?Disulfides?or?Diselenides?in?the?Presence?ofiodine,?J.?Org.?Chem.?2009,?74,?7844–7848.

38?Tao-Shan?Jiang,?Ri-Yuan?Tang,?Xing-Guo?Zhang,?Xin-Hua?Li,?Jin-Heng?Li*?Palladium-Catalyzed?Intramolecular?5-exo-dig?Hydroarylations?of?N-Arylpropiolamides:?thermodynamics-Controlled?Stereoselective?Synthesis?of?3-Methyleneoxindoles,?J.?Org.?Chem.?2009,?74,?8834-8837.

39?Wang,?Z.-Q.;?Tang,?B.-X.;?Zhang,?H.-P.;?Wang,?F.;?Li,?J.-H.*?Electrophilicipso-Halocyclization?of?N-Arylpropiolamides?with?Polyfluoroalkyl?Alcohols:?Selective?Synthesis?of?8-(Polyfluoroalkoxy)azaspiro[4,5]trienes,?Synthesis?2009,?891-902.

40?Luo,?P.-S.;?Wang,?F.;?Li?J.-H.;*?Tang,?R.-Y.;?Zhong,?P.*?Copper-Catalyzed?Selective?S-Arylation?of?1,2-Bis(o-amino-1H-pyrazolyl)disulfides?with?Arylboronic?Acids,?Synthesis?2009,?921-928.

41?Tao-Shan?Jiang,?Xing-Guo?Zhang,?and?Jin-Heng?Li*?Iodocyclization?of?N-(2-Methylthiophenyl)propiolamides:?Selective?Synthesis?of?3-Iodo-1,5-benzothiazepin-4-ones,?Synthesis?2009,?3029-3038.

42?Xiao-li?Fang,?Ri-Yuan?Tang,?Ping?Zhong,?Jin-Heng?Li*?Iron-Catalyzed?Sulfenylation?of?Indoles?with?Disulfides?Promoted?by?a?Catalytic?Amount?of?Iodine,?Synthesis?2009,?4183-4189.

43?Sha-Sha?Pi,?Xing-Guo?Zhang,?Ri-Yuan?Tang,?Jin-Heng?Li*?Copper-Catalyzed?Tandem?Reaction?of?2-Haloaniline?Derivatives?with?Tetraalkylthiuram?Disulfides:?Selective?Synthesis?of?2-Aminobenzothiazoles,?Synlett?2009,?3032-3036.

44?Luo,?P.-S.;?Yu,?M.?Tang,?R.-Y.;*?Zhong,?P.;?Li?J.-H.*?Solvent-free?copper-catalyzed?oxidative?S-arylation?of?1,2-diaryldisulfides?with?aryltrimethoxysilane,?Tetrahedron?Lett.?2009,?50,?1066-1070.

45?Ren-Jie?Song,?Yu?Liu,?Rong-Jiang?Li,?and?Li,?J.-H.*?Selective?synthesis?of?3-methyleneindolin-2-ones?by?one-pot?multicatalytic?processes,?Tetrahedron?Lett.?2009,?50,?3912-3916.

46?Yu,?M.;?Tang,?R.-Y.;?Li?J.-H.*?Synthesis?of?6,7-dihydro-5H-dibenzo[c,e]azepines?and?biaryls?by?palladiumcatalyzed?Ullmann?reaction,?Tetrahedron?2009,?65,?3409-3416.

47?Zhijuan?Cao,?Yulong?Hu,?Wei?Wu,?Tuanzhu?Ha,?Jim?Kelley,?Chenliang?Deng,?Qi?Chen,?Chuanfu?Li,?Jinheng?Li*,?and?Yuehua?Li*?The?TIR/BB-loopmimetic?AS-1?protects?the?myocardium?from?ischaemia/reperfusion?injury,?Cardiovascular?Research?2009,?84,?442–451.

48?TAO?Liming,?XIE?Yexiang,*?DENG?Chenliang,?LI?Jin-heng?*Generation?of?Pd?Nanoparticles?in?situ?from?PdCl2?in?TBAF:?an?Efficient?and?Reusable?Catalytic?System?for?the?Suzuki-Miyaura?Reaction?under?Ligand-?and?Solvent-free?Conditions,?Chin.?J.?Chem.?2009,?27,?1365-1373..

49?罗培松?汤日元?钟平,?李金恒,?炔烃分子内环化反应合成含氮杂环化合物研究进展,?有机化学,?2009,?29,?1924-1937.

50?Tang,?B.-X.;?Tang,?D.-J.;?Tang,?S.;?Yu?,?Q.-F.;?Zhang,?Y.-H.;?Liang,?Y.;?Zhong,?P.;?Li,?J.-H.*?Selective?Synthesis?of?Spiro[4,5]trienyl?Acetates?via?An?Intramolecular?Electrophilic?ipso-Iodocyclization?Process,?Org.?Lett.?2008,?10,?1063-1066.

51?Tang,?S.;?Peng,?P.;?Pi,?S.-F.;?Liang,?Y.;?Wang,?N.-X.;*?Li,?J.-H.*?Sequential?Intermolecular?Aminopalladation/ortho-Arene?C-H?Activation?Reactions?of?N-Phenylpropiolamides?with?Phthalimide,?Org.?Lett.?2008,?10,?1179-1182.

52?Huang,?X.-C.;?Liu,?Y.-L.;?Liang,?Y.;*?Pi,?S.-F.;?Wang,?F.;?Li,?J.-H.*?Cycloaddition?of?Arynes?with?Iodonium?Ylides:?A?Mild?and?General?Route?for?the?Synthesis?of?Benzofuran?Derivatives,?Org.?Lett.?2008,?10,?1525-1528.

53?Tang,?S.;?Peng,?P.;?Wang,?Z.-Q.;?Tang,?B.-X.;?Deng,?C.-L.;?Li,?J.-H.*;?Zhong,?P.;?Wang,?N.-X.?Synthesis?of?(2-Oxoindolin-3-ylidene)methyl?Acetates?Involving?a?C?H?Functionalization?Process,?Org.?Lett.?2008,?10,?1875-1878.

54?Yu,?Q.-F.;?Zhang,?Y.-H.;?Yin,?Q.;?Tang,?B.-X.;?Tang,?R.-Y.;?Ping?Zhong,?P.;?Li,?J.-H.*?Electrophilic?ipso-Iodocyclization?of?N-(4-Methylphenyl)propiolamides:?Selective?Synthesis?of?8-Methyleneazaspiro[4,5]trienes,?J.?Org.?Chem.?2008,?73,?3658-3661.

55?Tang,?S.;?Peng,?P.;?Zhong,?P.;?Li,?J.-H.*?Palladium-Catalyzed?C-H?Functionalization?of?N-Arylpropiolamides?with?Aryliodonium?Salts:?Selective?Synthesis?of?3-(1-Arylmethylene)oxindoles,?J.?Org.?Chem.?2008,?73,?5476-5480.

56?Tang,?B.-X.;?Yin,?Q.;?Tang,?R.-Y.;?Li,?J.-H.*?Electrophilic?ipso-Cyclization?of?N-(p-Methoxyaryl)propiolamides?Involving?An?Electrophile-Exchange?Process,?J.?Org.?Chem.?2008,?73,?9008–9011.

57?Tang,?B.-X.;?Guo,?S.-M.;?Zhang,?M.-B.;?Li,?J.-H.*?N-Arylations?of?Nitrogen-Containing?Heterocycles?with?Aryl?and?Heteroaryl?Halides?Using?Cu2O?Nanoparticles/1,10-Phenanthroline?Catalytic?System,?Synthesis?2008,?1707-1716.

58?Liang,?Y.;?Tao,?L.-M.;?Zhang,?Y.-H.;?Li,?J.-H.*?Palladium-Catalyzed?Cross-Coupling?Reactions?of?1,2-Diiodoalkenes?with?Terminal?Alkynes:?Selectively?Synthesis?of?Unsymmetric?1,3-Butadiynes?and?2-Ethynylbenzofurans,?Synthesis?2008,?3988.

59?Wang,?Z.-L.;?Tang,?R.-Y.;*?Luo,?P.-S.;?Deng,?C.-L.;?Zhong,?P.;?Li,?J.-H.*?Hydrothiolation?of?Terminal?Alkynes?with?Diaryl?Disulfides?and?Diphenyl?Diselenide:?Selective?Synthesis?of?(Z)-1-Alkenyl?Sulfides?and?Selenides,?Tetrahedron?2008,?64,?10670-10675.

60?Xie,?Y.-X.;?Wang,?J.;?Li,?J.-H.;*?Liang,?Y.*?Reusable?and?Ligand-Free?Palladium-Catalyzed?Suzuki-Miyaura?Cross-Couplings?of?Aryl?Halides?with?Arylboronic?Acids?inTBAB,?Chin.?J.?Chem.?2008,?26,?2261-2266.

61?Deng,?C.-L.;?Song,?R.-J.;?Guo,?S.-M.;?Wang,?Z.-Q.;?Li,?J.-H.*?Copper/Silver-Cocatalyzed?Conia-Ene?Reaction?of?Linear?b-Alkynic?b-Ketoesters,?Org.?Lett.?2007,?9,?5111-5114.

62?Tang,?S.;?Yu,?Q.-F.;?Peng,?P.;?Li,?J.-H.*;?Zhong,?P.;?Tang?R.-Y.?Palladium-Catalyzed?Carbonylative?Annulation?Reaction?of?2-(1-Alkynyl)benzenamines:?Selective?Synthesis?of?3-(Halomethylene)indolin-2-ones,?Org.?Lett.?2007,?9,?3413-3416.

63?Li,?J.-H.*;?Li,?J.-L.;?Wang,?D.-P.;?Pi,?S.-F.;?Xie,?Y.-X.;?Zhang?M.-B.;?Hu,?X.-C.?CuI-Catalyzed?Suzuki-Miyaura?andSonogashira?Cross-Coupling?Reactions?UsingDABCO?as?Ligand,?J.?Org.?Chem.?2007,?72,?2053-2057.

64?Tang,?B.-X.;?Wang,?F.;?Li,?J.-H.*;?Xie,?Y.-X.;?Zhang?M.-B.?Reusable?Cu2O/PPh3/TBAB?System?for?the?Cross-Couplings?of?Aryl?Halides?and?Heteroaryl?Halides?with?Terminal?Alkynes,?J.?Org.?Chem.?2007,?72,?6294-6297.

65?Liang,?Y.;?Xie,?Y.-X.;?Li,?J.-H.*?Cy2NH×HX-Promoted?Cyclizations?of?o-(1-Alkynyl)benzoates?and?(Z)-2-Alken-4-ynoate?with?Copper?Halides?to?synthesize?Isocoumarins?and?a-Pyrone,?Synthesis?2007,?400-406.

66?Li,?J.-H.*;?Li,?J.-L.;?Xie,?Y.-X.?TBAB-Promoted?Ligand-Free?Copper-Catalyzed?Cross-Coupling?Reactions?of?Aryl?Halides?with?Arylboronic?Acids,?Synthesis?2007,?984-988.

67?Tang,?S.;?Li,?J.-H.*;?Xie,?Y.-X.;?Wang?N.-X.*?Halogenations?of?Indoles?with?CuX2:?Selective?Synthesis?of?2-Halo-,?3-Halo-?and?2,3-Dibromoindoles,?Synthesis?2007,?1535-1541.

68?Tang,?S.;?Xie,?Y.-X.;?Li,?J.-H.*;?Wang?N.-X.*?PdX2/CuX2-Catalyzed?Annulation?of?2-Ethynylbenzenamines:?Selective?Synthesis?of?3-Halo-2-substituted-1H-indoles,?Synthesis?2007,?1841-1847.

69?Li,?J.-H.*;?Zhang,?Y.-H.;?Song,?R.-J.;?Xie,?Y.-X.;?Deng,?C.-L.;?Liang,?Y.?b-Keto?Amides:inexpensive?and?Efficient?Ligands?for?the?Palladium-Catalyzed?Suzuki-Miyaura?Cross-Coupling?Reaction,?Synthesis?2007,?2957-2966.

70?Deng,?C.-L.;?Guo,?S.-M.;?Xie,?Y.-X.;?Li,?J.-H.*?Mild?and?ligand-free?palladium-catalyzed?cross-couplings?of?aryl?halides?with?arylboronic?acids?to?synthesize?biaryls?and?heterocycle-containing?biaryls,?Eur.?J.?Org.?Chem.?2007,?1457-1462.

71?Song,?R.-J.;?Deng,?C.-L.;?Xie,?Y.-X.;?Li,?J.-H.*?Solvent-free?copper/iron?co-catalyzed?N-arylation?reactions?of?nitrogen-containing?heterocycles?with?trimethoxysilanes?in?air,?Tetrahedron?Lett.?2007,?44,?7845-7848.

72?Guo,?S.-M.;?Deng,?C.-L.;?Li,?J.-H.*?Cu(OAc)2-Catalyzed?Sonogashira?Cross-coupling?Reaction?in?Amines,?Chin.?Chem.?Lett.?2007,?18,?13-16.

73?Li,?J.-H.*;?Deng,?C.-L.;?Xie,?Y.-X.?Solvent-Free?Palladium-Catalyzed?Suzuki-Miyaura?Cross-Couplings?of?Aryl?Chlorides?with?Arylboronic?Acids,?Synth.?Commun.?2007,?37,?2433-2448.

74?唐石，王乃兴*，李金恒*，不饱和烃Heteropalladation反应在有机合成中的应用，有机化学，2007，27，819-829.

75?陶李明，梁云，李金恒*，末端炔烃二聚反应合成共轭烯炔的研究进展，有机化学，2007，27，1078-1086.

76?Liang,?Y.;?Tang,?S.;?Zhang,?X.-D.;?Mao,?L.-Q.;?Xie,?Y.-X.;?Li,?J.-H.*?Novel?and?Selective?Palladium-Catalyzed?Annulations?of?2-Alkynylphenols?To?Form?2-Substituted?3-Halobenzo[b]furans,?Org.?Lett.?2006,?8,?3017-3020.

77?Liang,?Y.;?Xie,?Y.-X.;?Li,?J.-H.*?General?and?Modified?Palladium-Catalyzed?Sonogashira?Cross-Coupling?Reaction?under?Copper-,?Amine-?and?Solvent-Free?Conditions,?J.?Org.?Chem.?2006,?71,?379-381.

78?Li,?J.-H.*;?Tang,?B.-X.;?Tao,?L.-M.;?Liang,?Y.;?Zhang,?M.-B.*?Reusable?Copper-Catalyzed?Cross-Coupling?Reactions?of?Aryl?Halides?with?Organotins?in?Inexpensive?Ionic?Liquids,?J.?Org.?Chem.?2006,?71,?7488-7490.

79?Xie,?Y.-X.;?Pi,?S.-F.;?Wang,?J.;?Yin,?D.-L.;?Li,?J.-H.*?2-Aminopyrimidine-4,6-diol?as?an?Efficient?Ligand?for?Solvent-Free?Copper-Catalyzed?N-Arylations?of?Imidazoles?with?Aryl?and?Heteroaryl?Halides,?J.?Org.?Chem.?2006,?71,?8324-8327.

80?Liu,?W.-J.;?Xie,?Y.-X.;?Liang,?Y.;?Li,?J.-H.*?Reusable?and?Efficient?Pd(OAc)2/TBAB/PEG-400?System?for?Suzuki-Miyaura?Cross-Coupling?Reaction?Under?Ligand-Free?Conditions,?Synthesis?2006,?860-864.

81?Li,?J.-H.;*?Deng,?C.-L.;?Xie,?Y.-X.?Improved?Procedure?for?Palladium-Catalyzed?Hiyama?Cross-Coupling?Reaction?of?Aryl?Halides?with?Aryltrimethoxysilanes?under?Solvent-Free?Conditions,?Synthesis?2006,?969-974.

82?Deng,?C.-L.;?Xie,?Y.-X.;?Yin,?D.-L.?Li,?J.-H.*?Cu(OAc)2/DAB-Ph-Catalyzed?Sonogashira?Cross-Couplings?of?Aryl?Halides?with?Terminal?Alkynes?under?Aerobic?and?Solvent-Free?Conditions,?Synthesis?2006,?3370-3376.

83?Li,?J.-H.;*?Hu,?X.-C.;?Liang,?Y.;?Xie,?Y.-X.?PEG-400?Promoted?Pd(OAc)2/DABCO-Catalyzed?Cross-Coupling?Reaction?in?Aqueous?Media,?Tetrahedron?2006,?62,?31-38.

84?Li,?J.-H.;*?Zhu,?Q.-M.;?Xie,?Y.-X.?Pd(OAc)2/DABCO-catalyzed?Suzuki-Miyaura?cross-coupling?reaction?in?DMF,?Tetrahedron?2006,?62,?10888-10895.

85?Li,?J.-H.;*?Hu,?Q.-C.;?Xie,?Y.-X.?Polymer-Supported?DABCO-Palladium?Complex?as?A?Stable?and?Reusable?Catalyst?for?Room?Temperature?Suzuki-Miyaura?Cross-Couplings?of?Aryl?Bromides,?Tetrahedron?Lett.?2006,?47,?9239-9243.

86?Li,?J.-H.;*?Wang,?D.-P.?CuI/DABCO-catalyzed?cross-coupling?reactions?of?aryl?halides?with?arylboronic?acids,?Eur.?J.?Org.?Chem.?2006,?2063-2066.

87?Gao,?Q.;?Zheng,?B.-F.;?Li,?J.-H.;?Yang,?D.*?Ni(II)-Catalyzed?Conia-Ene?Reaction?of?1,3-Dicarbonyl?Compounds?with?Alkynes,?Org.?Lett.?2005,?7,?2185-2188.

88?Yip,?K.-T.;?Li,?J.-H.;?Lee,?O.-Y.;?Yang,?D.*?Aerobic?Oxidative?Cyclization?under?Pd(II)?Catalysis:?A?Regioselective?Approach?to?Heterocycles,?Org.?Lett.?2005?7,?5717-5719.

89?Li,?J.-H.;*?Tang,?S.;?Xie,?Y.-X.?General?and?Selective?Synthesis?of?(Z)-3-Haloacrylates?via?Palladium-Catalyzed?Carbonylation?of?Terminal?Alkynes,?J.?Org.?Chem.?2005,?70,?477-479.

90?Li,?J.-H.;*?Liang,?Y.;?Wang,?D.-P.;?Liu,?W.-J.;?Xie,?Y.-X.;?Yin,?D.-L.?Efficient?Stille?Cross-Coupling?Reaction?Catalyzed?by?Pd(OAc)2/Dabco?Catalytic?System,?J.?Org.?Chem.?2005,?70,?2832-2834.

91?Li,?J.-H.;*?Liang,?Y.;?Xie,?Y.-X.?Efficient?Palladium-Catalyzed?Homocoupling?Reaction?and?Sonogashira?Cross-Coupling?Reaction?of?Terminal?Alkynes?under?Aerobic?Conditions.?J.?Org.?Chem.?2005,?70,?4393-4396.

92?Li,?J.-H.;*?Zhu,?Q.-M.;?Liang,?Y.;?Yang?D.?Efficient?and?Reusable?PdCl2(MECN)2/CuCl2/PEG-400?System?for?Cyclization?of?Alkenyl?Keto?Esters?and?Amides,?J.?Org.?Chem.?2005,?70,?5347-5349.

93?Li,?J.-H.;*?Liu,?W.-J.;?Xie,?Y.-X.?Recyclable?and?Reusable?Pd(OAc)2/DABCO/PEG-400?System?for?Suzuki-Miyaura?Cross-Coupling?Reaction,?J.?Org.?Chem.?2005,?70,?5409-5412.

94?Li,?J.-H.;*?Wang,?D.-P.;?Xie,?Y.-X.?CuI/Dabco?as?a?Highly?Active?Catalytic?System?for?the?Heck-Type?Reaction,?Tetrahedron?Lett.?2005,?46,?4941-4944.

95?Li,?J.-H.;*?Liang,?Y.;?Zhang,?X.-D.?Amine-?and?phosphine-free?palladium(II)-catalyzed?homocoupling?reaction?of?terminal?alkynes,?Tetrahedron?2005,?61,?1903-1907.

96?Li,?J.-H.;*?Liang,?Y.;?Xie,?Y.-X.?Efficient?Stille?Cross-Coupling?Reaction?Catalyzed?by?Pd(OAc)2/DAB-Cy?Catalytic?System,?Tetrahedron?2005,?61,?7289-7293.

97?Li,?J.-H.;*?Zhang,?X.-D.;?Xie,?Y.-X.?Efficient?and?Copper-Free?Pd(OAc)2/Dabco-catalyzed?Sonogashira?Cross-Coupling?Reaction,?Synthesis?2005,?804-808.

98?Li,?J.-H.;*?Wang,?D.-P.;?Xie,?Y.-X.?Pd(OAc)2/Dabco?as?a?Highly?Active?Catalytic?System?for?the?Heck?Reaction,?Synthesis?2005,?2193-2197.

99?Li,?J.-H.;*?Deng,?C.-L.;?Liu,?W.-J.;?Xie,?Y.-X.?Pd(OAc)2/DABCO?as?an?Inexpensive?and?Efficient?Catalytic?System?for?Hiyama?Cross-Coupling?Reactions?of?Aryl?Halides?with?Aryltrimethoxysilanes,?Synthesis?2005,?3039-3044.

100?Li,?J.-H.;*?Zhang,?X.-D.;?Xie,?Y.-X.?Efficient?Pd(OAc)2/Pyrimidines?Catalytic?System?for?Suzuki-Miyaura?Cross-Coupling?Reaction,?Synlett?2005,?1897-1900.

101?Li,?J.-H.;*?Zhang,?X.-D.;?Xie,?Y.-X.?Efficient?and?copper-free?Sonogashira?cross-coupling?reaction?catalyzed?by?Pd(OAc)2/pyrimidines?catalytic?system,?Eur.?J.?Org.?Chem.?2005,?4256-4259.

102?Li,?J.-H.;*?Liu,?W.-J.?Dabco?as?an?Inexpensive?and?Highly?Efficient?Ligand?for?Palladium-Catalyzed?Suzuki-Miyaura?Cross-Coupling?Reaction,?Org.?Lett.?2004,?6,?2809-2811.

103?Li,?J.-H.;*?Liang,?Y.;?Xie,?Y.-X.?Mild?and?Selective?Palladium-Catalyzed?Dimerization?of?Terminal?Alkynes?To?Form?(Z,Z)-1,4-Dihalo-1,3-dienes,?J.?Org.?Chem.?2004,?69,?8125-8127.

104?Li,?J.-H.;*?Xie,?Y.-X.;?Yin,?D.-L.?New?Role?of?CO2?as?A?Selective?Agent?in?Palladium-Catalyzed?Reductive?Ullmann?Coupling?with?Zinc?in?Water,?J.?Org.?Chem.?2003,?68,?9867-9869.

105?Li,?J.-H.;*?Xie,?Y.-X.;?Jiang,?H.-F.;?Chen,?M.-C.?Palladium-Catalyze?Ullmann-Type?Coupling?with?Zinc?in?the?Presence?of?H2O?in?Liquid?Carbon?Dioxide,?Green?Chem.?2002,?4,?424.

106?Li,?J.-H.;*?Xie,?Y.-X.;?Yin,?D.-L.?New?role?of?carbon?dioxide?in?Lewis?assisted?Brosted?acid?accelerated?diiodination?of?alkynes?in?water,?Green?Chem.2002,?4,?505.

107?Yang,?D.;*?Li,?J.-H.;?Gao,?Q.;?Yan,?Y.-L.lanthanide?Triflates?Promoted?Palladium-Catalyzed?Cyclization?of?Alkenyl?b–Keto?Esters?and?Amides,?Org.?Lett.?2003,?5,?2869-2871.

108?Li,?J.-H.;?Jiang,?H.-F.;?*?Chen,?M.-C.?CuCl2-induced?regiospecifical?synthesis?of?benzene?derivatives?in?the?palladium-catalyzed?cyclotrimerization?of?alkynes,?J.?Org.?Chem.?2001,?66,?3627-3629.

109?Li,?J.-H.;?Jiang,?H.-F.;*?Chen,?M.-C.*respective?conversion?of?n-butylamine?to?methyl?N-n-butylcarbamate?and?oxalbutyline?in?supercritical?carbon?dioxide,?Green?Chem.?2001,?3,?137.

110?Li,?G.-P.;?Jiang,?H.-F.;*?Li,?J.-H.?Use?Water?as?a?Direct?Hydrogendonor?in?Supercritical?Carbon?Dioxide:?A?Novel?and?Efficient?Zn-H2O-CO2?System?for?Selective?Reduction?of?Aldehydes?to?Alcohols,?Green?Chem.?2001,?3,?250.

111?Li,?J.-H.;?Li,?G.-P.;?Jiang,?H.-F.;*?Chen,?M.-C.*?A?novel?and?efficient?synthesis?of?maleic?anhydrides?by?palladium-catalyzed?dicarbonylation?of?terminal?acetylenes?in?H2O/Dioxane,?Tetrahedron?Lett.?2001,?42,?6923-6924.

112?Li,?J.-H.;?Jiang,?H.-F.;*?Feng,?A.-Q.;?Jia,?L.-Q.?Novel?stereospecific?syntheses?of?3-chloroacrylate?esters?via?palladium-catalyzed?carbonylation?of?terminal?acetylenes.?J.?Org.?Chem.?1999,?64,?5984-5987.

113?Jia,?L.-Q.;?Jiang,?H.-F.;*?Li,?J.-H.?Palladium(Ⅱ)-catalyzed?oxidation?of?acrylate?esters?to?acetals?in?supercritical?carbon?dioxide.?Chem.?Commun.?1999,?985.

114?Li,?J.-H.;?Jiang,?H.-F.;*?Jia,?L.-Q.?Glasser?coupling?reaction?in?supercritical?carbon?dioxide,?Chem.?Commun.?1999,?2369.

115?Jia,?L.-Q.;?Jiang,?H.-F.;*?Li,?J.-H.?Selective?carbonylation?of?norbornene?in?scCO2:?palladium(II)-catalyzed?carbonylation?of?norbornene?in?supercritical?carbon?dioxide.?Green?Chem.?1999,?1,?91.